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UHRF1BP1 Antibody#25348

UHRF1BP1 Antibody
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产品详情

产品名称UHRF1BP1 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Affinity chromatography purified via peptide column

应用ELISA WB

种属反应性Hu Ms

特异性UHRF1BP1 antibody is predicted to not cross-react with UHRF1BP1L

免疫原类型Peptide

免疫原描述Raised against a 17 amino acid peptide near the center of human UHRF1BP1.

基因/蛋白名称UHRF1BP1

别名Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1, ICBP90-binding protein 1, UHRF1 binding protein 1

数据库入口号NP_060224

UniprotNP_060224

浓度1mg/ml

配方Supplied in PBS containing 0.02% sodium azide.

保存Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western blot analysis of UHRF1BP1 in mouse kidney tissue lysate with UHRF1BP1 antibody at (A) 1 and (B) 2 ug/mL.
背景
The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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025-58868422

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