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位置: 首页 > 抗体 > EGFR(Ab-1092) Antibody

EGFR(Ab-1092) Antibody#21074

EGFR(Ab-1092) Antibody
EGFR(Ab-1092) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称EGFR(Ab-1092) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB IHC

种属反应性Hu Rt

特异性The antibody detects endogenous level of total EGFR protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa. 1090~1094 (P-E-Y-I-N) derived from Human EGFR.

基因/蛋白名称EGFR

别名 Receptor tyrosine-protein kinase ErbB-1

数据库入口号Swiss-Prot: P00533
NCBI Protein: NP_005219.2

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情
Predicted MW: 175kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Western blot analysis of extracts from HepG2, 293 and Hela cells using EGFR(Ab-1092) Antibody #21074.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using EGFR(Ab-1092) Antibody #21074(left) or the same antibody preincubated with blocking peptide(right).
背景
Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia

Buerger C, et al. (2003) J Biol Chem; 278(39): 37610-21.
Wang XQ, (2003) J Biol Chem; 278(49): 48770-8.
Saito T, et al. (2004) Endocrinology; 145(9): 4232-43.
Pao W, et al. (2004) Proc Natl Acad Sci U S A; 101(36): 13306-11.
Mattila E, et al. (2005) Nat Cell Biol; 7(1): 78-85.

如果您使用该产品21074发表了文章,请通知我们,让我们可以引用您的文献。

et al,Cytoplasmic retention of a nucleocytoplasmic protein TBC1D3 by microtubule network is required for enhanced EGFR signaling.In PLoS One on 2014 Apr 8 by Ze He, Tian Tian et al..PMID:24714105, , (2014),
PMID: 24714105
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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