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位置: 首页 > 抗体 > IL18BP Antibody

IL18BP Antibody#31022

IL18BP Antibody
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产品总价:
产品详情

产品名称IL18BP Antibody

来源种属Rabbit

克隆性Polyclonal

应用ELISA WB

种属反应性Hu

特异性The antibody detects endogenous level of total IL18BP protein.

免疫原类型Recombinant Protein

免疫原描述Fusion protein corresponding to a region derived from 31-195 of human Interleukin-18-binding protein

基因/蛋白名称IL18BP

别名interleukin 18 binding protein, IL18BPa

数据库入口号Genbank No.: BC044215

UniprotBC044215

浓度0.8mg/ml

配方Supplied at 0.8mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Predicted MW: 21kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000

Gel: 10%SDS-PAGE
Lysate: 60 µg Human lymphoma tissue lysate
Primary antibody: 1/400 dilution
Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Exposure time: 30 seconds
背景

The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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025-58868422

Email Address

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