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位置: 首页 > 抗体 > JAK1(Ab-1022) Antibody

JAK1(Ab-1022) Antibody#21119

JAK1(Ab-1022) Antibody
JAK1(Ab-1022) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称JAK1(Ab-1022) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB IHC

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total JAK1 protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa. 1020~1024 (K-E-Y-Y-T) derived from Human JAK1.

基因/蛋白名称JAK1

别名 Janus kinase 1

数据库入口号Swiss-Prot: P23458
NCBI Protein: NP_002218.2

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情
Predicted MW: 130kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Western blot analysis of extracts from 3T3, HepG2, HT29 and MDA cells using JAK1(Ab-1022) Antibody #21119.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using JAK1(Ab-1022) Antibody #21119(left) or the same antibody preincubated with blocking peptide(right).
背景
Tyrosine kinase of the non-receptor type, involved in the IFN-a/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.

Zheng H, et al. (2005) Mol Cell Proteomics. 4(6):721-730.
Wang R, et al. (2003) Arch Biochem Biophys. 410(1): 7-15.

如果您使用该产品21119发表了文章,请通知我们,让我们可以引用您的文献。

et al,A thiazole-derived oridonIn analogue exhibits antitumor activity by directly and allosterically InhibitIng STAT3. In J Biol Chem on 2019 Nov 15;by Shen X, Zhao L,et al..PMID:31594861, , (2019),
PMID: 31594861
et al,Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway. In J Cancer Res Clin Oncol on 2011 Nov by Dan Liu, Yi Huang, et al..PMID:21861134, , (2011),
PMID: 21861134
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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