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CBFA1 Antibody#31165

CBFA1 Antibody
CBFA1 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称CBFA1 Antibody

来源种属Rabbit

克隆性Polyclonal

应用ELISA WB IHC

种属反应性Hu Ms

特异性The antibody detects endogenous level of total CBFA1 protein.

免疫原类型Peptide

免疫原描述Synthetic peptide corresponding to a region derived from 320-336 amino acids of Human Core-binding factor subunit alpha-1

基因/蛋白名称CBFA1

别名Core-binding factor subunit alpha-1 , CCD, AML3, CCD1, OSF2, OSF-2, PEA2aA, PEBP2A1, PEBP2A2, PEBP2aA, PEBP2aA1

数据库入口号Genbank No.: NP_004339.3

UniprotNP_004339.3

浓度1.0mg/ml

配方Supplied at 0.8mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Predicted MW: 54kd
ELISA: 1:500-1:5000
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:10-1:50

Gel: 10%SDS-PAGE
Lane1: Human renal cancer tissue lysate
Lane2: Human leg malignant fibrous histiotoma tissue lysate
Lysates: 10 ug per lane
Primary antibody: 1/400 dilution
Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/5000 dilution
Exposure time: 1 minute
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 31165(CBFA1 Antibody) at dilution 1/10, on the right is treated with the synthetic peptide.
背景

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com