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位置: 首页 > 标记抗体 > PPAR alpha (Phospho-Ser12) Antibody Biotin Conjugated

PPAR alpha (Phospho-Ser12) Antibody Biotin Conjugated#C05117B

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产品总价:
产品详情

产品名称PPAR alpha (Phospho-Ser12) Antibody Biotin Conjugated

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Purified by Protein A.

应用WB IHC-P

种属反应性Hu Ms Rt

免疫原描述KLH conjugated synthetic phosphopeptide aa 1-15 468 derived from human PPAR alpha around the phosphorylation site of ser12

标记Biotin

激发/发射波长N A

基因/蛋白名称PPAR alpha Ser12

别名PPAR; NR1C1; hPPAR; PPARalpha; Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1; PPARA

数据库入口号Swiss-Prot#Q07869
NCBI Gene ID5465

细胞定位Nucleus

浓度1mg/ml

配方10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.

保存 Store at 4C for 12 months.

应用详情

Western blotting: 1:100-1000
Immunohistochemistry1:100-500

背景

Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0 18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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