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P2RY12 Antibody#31255

P2RY12 Antibody
P2RY12 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称P2RY12 Antibody

来源种属Rabbit

克隆性Polyclonal

应用ELISA WB IHC

种属反应性Hu

特异性The antibody detects endogenous level of total P2RY12 protein.

免疫原类型Peptide

免疫原描述Synthetic peptide corresponding to a region derived from 11-24 amino acids of human purinergic receptor P2Y, G-protein coupled, 12

基因/蛋白名称P2RY12

别名purinergic receptor P2Y, G-protein coupled, 12, HORK3, P2Y12, ADPG-R, BDPLT8, SP1999, P2T(AC), P2Y(AC), P2Y(12)R, P2Y(ADP), P2Y(cyc)

UniprotQ9H244

浓度0.6mg/ml

配方Supplied at 0.8mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Predicted MW: 39kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Gel: 10+12% SDS-PAGE
Lane1: 293T celllysate
Lane2: Hela cell lysate
Lysates: 40ug per lane
Primary antibody: 1/400 dilution
Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/5000 dilution
Exposure time: 30 seconds
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 31255 (P2RY12 Antibody) at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification: ×200)
背景

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene.

如果您使用该产品31255发表了文章,请通知我们,让我们可以引用您的文献。

et al,Integrative Analysis of Single-Cell and Bulk Sequencing Data Depicting the Expression and Function of P2ry12 in Microglia Post Ischemia–Reperfusion Injury InInt J Mol SciOn2023 AprbyChenglong Wang, Li Peng et al..PMID:37047745, , (2023),
PMID: 37047745
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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