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GEMIN2 Antibody#31266

GEMIN2 Antibody
GEMIN2 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称GEMIN2 Antibody

来源种属Rabbit

克隆性Polyclonal

应用ELISA WB IHC

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total GEMIN2 protein.

免疫原类型Peptide

免疫原描述Synthetic peptide corresponding to a region derived from 264-280 amino acids of human gem (nuclear organelle) associated protein 2

基因/蛋白名称GEMIN2

别名gem (nuclear organelle) associated protein 2, SIP1, SIP1-delta

数据库入口号Genbank No.: NP_003607.1

UniprotNP_003607.1

浓度0.3mg/ml

配方Supplied at 1.3mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Predicted MW: 32kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200

Gel: 10%SDS-PAGE
Lane1: K562 cell lysate
Lane2: Hela cell lysate
Lysates: 40 ug per lane
Primary antibody: 1/400 dilution
Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Exposure time: 2 minutes
The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using 31266 (GEMIN2 Antibody) at dilution 1/40, on the right is treated with the synthetic peptide.
背景

This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com