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位置: 首页 > 抗体 > ERK1/2 Antibody

ERK1/2 Antibody #29162

ERK1/2 Antibody
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产品总价:
产品详情

产品名称ERK1/2 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Affinity-chromatography

应用WB IHC

种属反应性Hu Ms Rt

特异性ERK1/2 antibody detects endogenous levels of total ERK1/2

免疫原类型Peptide

免疫原描述A synthesized peptide derived from human ERK1/2

基因/蛋白名称ERK1/2

别名Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, p44-MAPK, Microtubule-associated protein 2 kinase extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kin

数据库入口号Swiss-Prot#: P27361/P28482

UniprotP27361/P28482

实际分子量42,44KD

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C/1 year

应用详情

 WB: 1:500~1:3000

   IHC: 1:50~1:200 
Western blot analysis on COLO205 cell lysate using ERK1/2 Antibody
背景

ERK1 p42 MAP kinase plays a critical role in the regulation of cell growth and differentiation. Activated by a wide variety of extracellular signals including growth and neurotrophic factors, cytokines, hormones and neurotransmitters.ERK2 p44 MAP kinase plays a critical role in the regulation of cell growth and differentiation. Acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.

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et al,Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signalingInMol MedOn2023 Mar 23byXu Cao?1?2,?Song Wu et al..PMID:?36959556, , (2023),
PMID: 36959556
et al,The synergic Inhibitory effects of dark tea (Camellia sInensis) extract and p38 Inhibition on the growth of pancreatic cancer cells. In J Cancer on 2019 Oct 21 by Zheng K, Zhao Q,et al..PMID:31777585, , (2019),
PMID: 31777585
et al,Inhibitory effects of eugenol on RANKL-induced osteoclast formation via attenuation of NF-魏 B and MAPK pathways.In Connect Tissue Res on 2015 Jun by Vishwa Deepak , Abe Kasonga et al..PMID:25405641, , (2015),
PMID: 25405641
Zhifeng Wei, Jian Yang, Yu-Feng Xia et al,Cardamonin Protects Septic Mice from Acute Lung Injury by Preventing Endothelial Barrier Dysfunction, J BIOCHEM MOLECULAR TOXICOLOGY, 26(7):282-290 (2012),
PMID: 22696397
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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