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位置: 首页 > 磷酸化抗体 > Ataxin 1 (Phospho-Ser776) Antibody

Ataxin 1 (Phospho-Ser776) Antibody#12034

Ataxin 1 (Phospho-Ser776) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Ataxin 1 (Phospho-Ser776) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms

特异性The antibody detects endogenous level of Ataxin 1 only when phosphorylated at Serine 776.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Serine 776 (R-W-S(p)-A-P) derived from Human Ataxin 1.

基因/蛋白名称Ataxin 1

修饰Phospho

别名ATX1, D6S504E, SCA1

数据库入口号Swiss-Prot#: P54253;
NCBI Gene#: 6310;
NCBI Protein#: NP_000323.2

UniprotP54253

实际分子量87kd

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情
Predicted MW: 87kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from HepG2 cells using Ataxin 1 (Phospho-Ser776) Antibody #12034.The lane on the left is treated with the antigen-specific peptide.
背景
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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