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位置: 首页 > 磷酸化抗体 > BCL-2 (Phospho-Thr69) Antibody

BCL-2 (Phospho-Thr69) Antibody#12036

BCL-2 (Phospho-Thr69) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称BCL-2 (Phospho-Thr69) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu

特异性The antibody detects endogenous level of BCL-2 only when phosphorylated at Threonine 69.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Threonine 69 (A-R-T(p)-S-P) derived from Human BCL-2.

基因/蛋白名称BCL-2

修饰Phospho

别名PPP1R50, BCL2

数据库入口号Swiss-Prot#: P10415;
NCBI Gene#: 596;
NCBI Protein#: NP_000624.2

UniprotP10415

实际分子量26kd

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情
Predicted MW: 26kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from Hela cells using BCL-2 (Phospho-Thr69) Antibody #12036.The lane on the left is treated with the antigen-specific peptide.
背景
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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025-58868422

Email Address

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