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位置: 首页 > 磷酸化抗体 > hnRNP C1/2 (Phospho-Ser260) Antibody

hnRNP C1/2 (Phospho-Ser260) Antibody#12048

hnRNP C1/2 (Phospho-Ser260) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称hnRNP C1/2 (Phospho-Ser260) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu

特异性The antibody detects endogenous level of hnRNP C1/2 only when phosphorylated at Serine 260.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Serine 260 (D-D-S(p)-A-E) derived from Human hnRNP C1/2.

基因/蛋白名称hnRNP C1/2

修饰Phospho

别名C1, C2, HNRNP, HNRPC, SNRPC

数据库入口号Swiss-Prot#: P07910;
NCBI Gene#: 3183;
NCBI Protein#: NP_001070910.1

UniprotP07910

实际分子量41kd

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情
Predicted MW: 41kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from 293 cells untreated or treated with H2O2 using hnRNP C1/2 (Phospho-Ser260) Antibody #12048.
背景
Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com