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GADD153 Antibody#29163

GADD153 Antibody
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产品总价:
产品详情

产品名称GADD153 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Immunogen affinity purified

应用WB IHC IF/ICC

种属反应性Hu Ms Rt

特异性GADD153 Antibody detects endogenous levels of GADD153

免疫原类型Peptide

免疫原描述A synthesized peptide derived from human GADD153

基因/蛋白名称GADD153

别名C/EBP-homologous protein, DDIT3, DNA-damage inducible transcript 3, GADD153, Growth arrest and DNA-damage-inducible protein GADD153 Molecular weight: 19174.8 chop

数据库入口号Swiss-Prot#: P35638

UniprotP35638

实际分子量26KD

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C/1 year

应用详情

WB: 1:500-1:2000

IHC: 1:50-1:200
IF/ICC: 1:100-1:500
Western blot analysis on Jurkat cell lysate using GADD153 Antibody
背景

 CHOP a transcriptional-regulatory protein of the bZIP family. Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA. May play an important role in melanoma progression. CK2-mediated phosphorylation inhibits its transcriptional activity. Up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform.

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et al,Achyranthes bidentata polysaccharides alleviate endoplasmic reticulum stress in osteoarthritis via lncRNA NEAT1/miR-377-3p pathway. In Biomed Pharmacother on 2022 Oct by Changlong Fu, Zhiwei Qiu,et al..PMID:35988424, , (2022),
PMID: 35988424
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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