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位置: 首页 > 单克隆抗体 > Bmi1 Monoclonal Antibody

Bmi1 Monoclonal Antibody#27170

Bmi1 Monoclonal Antibody
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产品总价:
产品详情

产品名称Bmi1 Monoclonal Antibody

来源种属Mouse

克隆性Monoclonal

克隆号10B1-D1

亚型IgG1

纯化Affinity purified

应用WB

种属反应性Hu

特异性This antibody detects endogenous levels of Bmi1 and does not cross-react with related proteins.

免疫原类型Recombinant Protein

免疫原描述Purified recombinant human Bmi1 protein fragments expressed in E.coli.

基因/蛋白名称Bmi1

别名B lymphoma Mo MLV insertion region (mouse); B lymphoma Mo MLV insertion region 1 homolog;Bmi 1; BMI1; BMI1 polycomb ring finger oncogene; BMI1_HUMAN; Flvi 2/bmi 1; FLVI2/BMI1; MGC12685; Murine leukemia viral (bmi 1) oncogene homolog;Oncogene BMI 1; PCGF 4

数据库入口号UniProt: P35226

Gene ID: 648

UniprotP35226

实际分子量43kd

配方Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine(pH 7.4,150 mM NaCl)with 0.2% sodium azide,0.1mg/mlBSA and 50% glycerol.

保存store at -20˚C

应用详情

Western blotting: 1:1000

Western blot detection of Bmi1 antibody in Hela,A549 and 293T cell lysates using Bmi1 antibody (1:1000 diluted).Predicted band size:43KDa.Observed band size:43KDa.
背景

 Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com