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位置: 首页 > 单克隆抗体 > GRB2 Monoclonal Antibody

GRB2 Monoclonal Antibody#27180

GRB2 Monoclonal Antibody
GRB2 Monoclonal Antibody
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产品总价:
产品详情

产品名称GRB2 Monoclonal Antibody

来源种属Mouse

克隆性Monoclonal

克隆号3B2-G2-E5

亚型IgG1

应用WB

种属反应性Hu Rt Ms Mk

特异性This antibody detects endogenous levels of GRB2 and does not cross-react with related proteins.

免疫原类型Recombinant Protein

免疫原描述Purified recombinant human GRB2 protein fragments expressed in E.coli.

基因/蛋白名称GRB2

别名Abundant SRC homology; Adapter protein GRB2; ASH; Ash protein; EGFRBP GRB2; Epidermal growth factor receptor binding protein; Epidermal growth factor receptor binding protein GRB2; GRB 2; GRB2 adapter protein; Grb2; GRB2_HUMAN; Grb3 3;

数据库入口号Uniprot: P62993

Gene ID: 2885

UniprotP62993

实际分子量25kd

配方Ascites

保存store at -20˚C

应用详情

 Western blotting: 1:500

Western blot detection of GRB2 in Jurkat,Raji,PC-12&3T3 cell lysates and using GRB2 antibody(1:500 diluted).Predicted band size: 25KDa Observed band size: 25KDa
Western blot detection of GRB2 in MCF7,3T3,COS7,C6 and Hela cell lysates and using GRB2 antibody(1:300 diluted).Predicted band size: 25KDa.Observed band size: 25KDa.
背景

 Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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400-9961-933
025-58868422

Email Address

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