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位置: 首页 > 单克隆抗体 > DR5 Monoclonal Antibody

DR5 Monoclonal Antibody#27200

DR5 Monoclonal Antibody
DR5 Monoclonal Antibody
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产品总价:
产品详情

产品名称DR5 Monoclonal Antibody

来源种属Mouse

克隆性Monoclonal

克隆号7F4-F8-G11

亚型IgG1

纯化Affinity purified

应用WB ICC

种属反应性Hu Ms

特异性This antibody detects endogenous levels of TNFRSF10B and does not cross-react with related proteins.

免疫原类型Recombinant Protein

免疫原描述Purified recombinant human TNFRSF10B protein fragments expressed in E.coli.

基因/蛋白名称DR5

别名Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L;

数据库入口号Uniprot: O14763

Gene ID: 8795

UniprotO14763

实际分子量48kd

配方Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.

保存store at -20˚C

应用详情

Western blotting: 1:500-1:2000

Immunocytochemistry: 1:100
Immunocytochemistry of HeLa cells fixed by Paraformaldehyde and using anti-TNFRSF10B antibody diluted 1:100.
Western blot detection of TNFRSF10B antibody in Mouse kindey,Mouse brain,HCT116 and Hela cell lysates using TNFRSF10B antibody (1:500-1:2000 diluted).Predicted band size:40/48KDa.Observed band size:40/48KDa.
背景

 Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor.The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.Essential for ER stress-induced apoptosis.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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400-9961-933
025-58868422

Email Address

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