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位置: 首页 > 单克隆抗体 > hHR23b Monoclonal Antibody

hHR23b Monoclonal Antibody#27219

hHR23b Monoclonal Antibody
hHR23b Monoclonal Antibody
hHR23b Monoclonal Antibody
hHR23b Monoclonal Antibody
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产品总价:
产品详情

产品名称hHR23b Monoclonal Antibody

来源种属Mouse

克隆性Monoclonal

克隆号5H1-A10-A7

亚型IgG2b

纯化Affinity purified

应用WB ICC IHC

种属反应性Hu Ms Rt Mk Hm

特异性This antibody detects endogenous levels of hHR23b and does not cross-react with related proteins.

免疫原类型Recombinant Protein

免疫原描述Purified recombinant human hHR23b protein fragments expressed in E.coli.

基因/蛋白名称hHR23b

别名homolog of B; RAD23B; RD23B_HUMAN; UV excision repair protein RAD23 homolog B; XP C repair complementing complex 58 kDa; XP C repair complementing complex 58 kDa protein; XP C repair complementing protein; XP-C repair-complementing complex 58 kDa protein;

数据库入口号Uniprot: P54727

Gene ID: 5887

UniprotP54727

实际分子量58kd

配方Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

保存store at -20˚C

应用详情

Western blotting: 1:1000

Immunocytochemistry: 1:100

Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using anti-hHR23b antibody (dilution 1:100).
Western blot detection of hHR23b in A431,K562,Jurkat,C6,3T3 and Hela cell lysates using hHR23b antibody (1:1000 diluted).Predicted band size:58KDa.Observed band size:58KDa.Exposure time:5min.
Immunohistochemical analysis of paraffin-embedded Prostate Cancer using hHR23b Mouse mAb (1/100 dilution).Antigen retrieval was performed by pressure cooking in citrate buffer (pH 6.0).
Western blot detection of hHR23b in K562,SW480,CHO-K1,3T3 and COS7 cell lysates using hHR23b antibody (1:1000 diluted).Predicted band size:58KDa.Observed band size:58KDa.Exposure time:5min.
背景

Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome.
 

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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