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位置: 首页 > 抗体 > FHL2 Antibody

FHL2 Antibody#21692

FHL2 Antibody
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产品总价:
产品详情

产品名称FHL2 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB

种属反应性Hu Ms

特异性The antibody detects endogenous level of total FHL2 protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.16~28 (I-L-R-E-E) derived from Human FHL2.

基因/蛋白名称FHL2

别名SLIM3; AAG11; FHL-2; DRAL; aging-associated gene 11

数据库入口号Swiss-Prot: Q14192 NCBI Protein: NP_001034581.1

UniprotQ14192

实际分子量32kd

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C

应用详情

 Western blotting: 1:500~1:1000

Western blot analysis of extracts from mouse brain tissue using FLH2 Antibody  #21692.
背景

 May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. 

Genini M., Schwalbe P., Scholl F.A., Remppis A., Mattei M.-G., Schaefer B.W.DNA Cell Biol. 16:433-442(1997)
Tanahashi H., Tabira T.Hum. Mol. Genet. 9:2281-2289(2000)

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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