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位置: 首页 > 磷酸化抗体 > HER2 (Phospho-Tyr1112) Antibody

HER2 (Phospho-Tyr1112) Antibody#11903

HER2 (Phospho-Tyr1112) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称HER2 (Phospho-Tyr1112) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu

特异性The antibody detects endogenous level of HER2 only when phosphorylated at tyrosine 1112.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of tyrosine 1112 (Q-R-Y(p)-S-E) derived from Human HER2.

基因/蛋白名称HER2

修饰Phospho

别名C-erbB-2; NGL; NEU proto-oncogene; MLN 19;

数据库入口号Swiss-Prot#: P04626;
NCBI Gene#: 2064;
NCBI Protein#: NP_001005862.1

UniprotP04626

实际分子量150kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情
Western blotting: 1:500~1:1000
Western blot analysis of extracts from HepG2 tissue using HER2 (Phospho-Tyr1112) antibody #11903.The lane on the right is treated with the antigen-specific peptide.
背景

Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-alpha and amphiregulin.

Chuang TD, et al. (2010)J Biol Chem 285, 23598-606
Bhuvaneswari R, Gan YY, Soo KC, Olivo M (2009) Mol Cancer 8, 94
Thelemann A, et al. (2005) Mol Cell Proteomics 4, 356-76

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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