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位置: 首页 > 磷酸化抗体 > Adrenergic Receptor beta2 (Phospho-Ser346) Antibody

Adrenergic Receptor beta2 (Phospho-Ser346) Antibody#11970

Adrenergic Receptor beta2 (Phospho-Ser346) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Adrenergic Receptor beta2 (Phospho-Ser346) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu

特异性The antibody detects endogenous level of Adrenergic Receptor beta2 only when phosphorylated at serine 346.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of serine 346 (R-S-S(p)-L-K) derived from Human Adrenergic Receptor beta2.

基因/蛋白名称Adrenergic Receptor beta2

修饰Phospho

别名ADRB2R; B2AR; adrenergic receptor; beta-2;

数据库入口号Swiss-Prot#: P07550;
NCBI Gene#: 154;
NCBI Protein#: NP_000015.1

UniprotP07550

实际分子量40kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Western blotting: 1:500~1:1000

Western blot analysis of extracts from HepG2 cells treated with Nocodazole using Phospho-Adrenergic Receptor beta2 (Ser346) antibody #11970.The lane on the right is treated with the antigen-specific peptide.
背景

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

Gao S, Malbon C, Wang HY (2014) J Mol Signal 9, 3
24690384 Curated Info
Vistein R, Puthenveedu MA (2013) Proc Natl Acad Sci U S A 110, 15289-94
Gimenez LE, et al. (2012) J Biol Chem 287, 9028-40

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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