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位置: 首页 > 磷酸化抗体 > VEGFR1 (Phospho-Tyr1213) Antibody

VEGFR1 (Phospho-Tyr1213) Antibody#11985

VEGFR1 (Phospho-Tyr1213) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称VEGFR1 (Phospho-Tyr1213) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of VEGFR1 only when phosphorylated at tyrosine 1213.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Tyrosine 1213(V-R-Y(p)-V-N) derived from Human VEGFR1.

基因/蛋白名称VEGFR1

修饰Phospho

别名FLT; FLT1; FRT; Flt-1; Fms-like tyrosine kinase 1

数据库入口号Swiss-Prot#: P17948;
NCBI Gene#: 2321;
NCBI Protein#: NP_001153392.1

UniprotP17948

实际分子量90kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情
Western blotting: 1:500~1:1000
Western blot analysis of extracts from HeLa cells treated with UV using Phospho-VEGFR1 (Tyr1213) antibody #11985.The lane on the right is treated with the antigen-specific peptide.
背景

Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.

Raghu H, et al. (2012) Mol Oncol 6, 33-47
Ito N, Huang K, Claesson-Welsh L (2001) Cell Signal 13, 849-54
Ito N, Wernstedt C, Engstr?m U, Claesson-Welsh L (1998) J Biol Chem 273, 23410-8

如果您使用该产品11985发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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