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位置: 首页 > 磷酸化抗体 > CCR5 (Phospho-Ser349) Antibody

CCR5 (Phospho-Ser349) Antibody#11650

CCR5 (Phospho-Ser349) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称CCR5 (Phospho-Ser349) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu

特异性The antibody detects endogenous levels of CCR5 only when phosphorylated at serine 349.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Serine 349 (E-I-S(p)-V-G) derived from Human CCR5.

基因/蛋白名称CCR5

修饰Phospho

别名C-C CKR-5; CKR5; CHEMR13; CMKBR5; CCR-5

数据库入口号Swiss-Prot#: P51681;
NCBI Gene#: 1234/727797;
NCBI Protein#: NP_000570.1.

UniprotP51681

实际分子量40kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Western blotting: 1:500~1:1000

Western blot analysis of extracts from A549 cells (Lane 2), using CCR5 (Phospho-Ser349) Antibody #11650. The lane on the left is treated with antigen-specific peptide.
背景

Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.

Martin Oppermann, J. Biol. Chem., Mar 1999; 274: 8875.
Beatrix Pollok-Kopp, J. Biol. Chem., Jan 2003; 278: 2190 - 2198.
Ramtin Rahbar, J. Virol., Jul 2006; 80: 7245 - 7259.
H Olbrich, J. Leukoc. Biol., Mar 1999; 65: 281.

如果您使用该产品11650发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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Email Address

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