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位置: 首页 > 磷酸化抗体 > CD32 (Phospho-Tyr292) Antibody

CD32 (Phospho-Tyr292) Antibody#11672

CD32 (Phospho-Tyr292) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称CD32 (Phospho-Tyr292) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu

特异性The antibody detects endogenous levels of CD32 only when phosphorylated at tyrosine 292.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32.

基因/蛋白名称CD32

修饰Phospho

别名CD32; FCG2; FCG2B,; LY-17; CDW32

数据库入口号Swiss-Prot#: P31994 ;
NCBI Gene#: 2213;
NCBI Protein#: NP_003992.3.

UniprotP31994

实际分子量32kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Western blotting: 1:500~1:1000

Western blot analysis of extracts from K562 cells treated with PMA using CD32 (Phospho-Tyr292) Antibody #11672.The lane on the right is treated with the antigen-specific peptide.
背景

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Stuart S.G., EMBO J. 8:3657-3666(1989).
Brooks D.G., J. Exp. Med. 170:1369-1385(1989).
Engelhardt W., Eur. J. Immunol. 20:1367-1377(1990).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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