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位置: 首页 > 磷酸化抗体 > Bax (Phospho-Thr167) Antibody

Bax (Phospho-Thr167) Antibody#11680

Bax (Phospho-Thr167) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Bax (Phospho-Thr167) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用IF

种属反应性Hu

特异性The antibody detects endogenous levels of Bax only when phosphorylated at threonine 167.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of threonine167 (P-G-T(p)-P-T) derived from Human Bax.

基因/蛋白名称Bax

修饰Phospho

别名 BAXA; Apoptosis regulator BAX; membrane isoform alpha; Bcl2-associated X protein;

数据库入口号Swiss-Prot#: Q07812;
NCBI Gene#: 581;
NCBI Protein#: NP_620116.1.

UniprotQ07812

实际分子量21kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Immunofluorescence: 1:100~1:200

Immunofluorescence staining of methanol-fixed A549 cells using Bax (Phospho-Thr167) Antibody #11680.
背景

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Francesca Andriani. J Natl Cancer Inst, Sep 2001; 93: 1314 - 1324.
H Martinez-Valdez. J. Exp. Med., Mar 1996; 183: 971.
Joslyn K. Brunelle. J. Biol. Chem., Feb 2004; 279: 4305 - 4312.

如果您使用该产品11680发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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