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位置: 首页 > 磷酸化抗体 > EPB41 (Phospho-Tyr660/418) Antibody

EPB41 (Phospho-Tyr660/418) Antibody#11799

EPB41 (Phospho-Tyr660/418) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称EPB41 (Phospho-Tyr660/418) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms

特异性The antibody detects endogenous levels of EPB41 only when phosphorylated at tyrosine 660/418.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of tyrosine 660/418 (N-I-Y(p)-I-R)derived from Human EPB41.

基因/蛋白名称EPB41

修饰Phospho

别名E41P; EPB4.1; band 4.1; P4.1;

数据库入口号Swiss-Prot#: P11171;
NCBI Gene#: 2035;
NCBI Protein#: NP_001159477.1.

UniprotP11171

实际分子量60kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Western blotting: 1:500~1:1000

Western blot analysis of extracts from HepG2 cells treated with PMA using EPB41 (Phospho-Tyr660/418) Antibody #11799.The lane on the right is treated with the antigen-specific peptide.
背景

Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.

Conboy J.G., Proc. Natl. Acad. Sci. U.S.A. 83:9512-9516(1986).
Tang T.K., Adv. Exp. Med. Biol. 241:81-95(1988).
Tang T.K., Proc. Natl. Acad. Sci. U.S.A. 85:3713-3717(1988).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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