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位置: 首页 > 磷酸化抗体 > TAL-1 (Phospho-Ser122) Antibody

TAL-1 (Phospho-Ser122) Antibody#11814

TAL-1 (Phospho-Ser122) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称TAL-1 (Phospho-Ser122) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms

特异性The antibody detects endogenous levels of TAL-1 only when phosphorylated at serine 122.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Serine 122(Q-L-S(p)-P-P) derived from Human TAL-1.

基因/蛋白名称TAL-1

修饰Phospho

别名SCL; TAL1; TCL5;

数据库入口号Swiss-Prot#: P17542;
NCBI Gene#: 6886;
NCBI Protein#: NP_001274276.1.

UniprotP17542

实际分子量45kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Western blotting: 1:500~1:1000

Western blot analysis of extracts from JK cells (Lane 2), using TAL-1 (Phospho-Ser122) Antibody #11814. The lane on the left is treated with antigen-specific peptide.
背景

TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.

Aplan P.D., Mol. Cell. Biol. 10:6426-6435(1990).
Gregory S.G., Nature 441:315-321(2006).
Chen Q., J. Exp. Med. 172:1403-1408(1990).

如果您使用该产品11814发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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