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位置: 首页 > 磷酸化抗体 > HDAC7A (Phospho-Ser155) Antibody

HDAC7A (Phospho-Ser155) Antibody#11823

HDAC7A (Phospho-Ser155) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称HDAC7A (Phospho-Ser155) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms

特异性The antibody detects endogenous levels of HDAC7A only when phosphorylated at serine 155.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Serine 155(T-V-S(p)-E-P) derived from Human HDAC7A.

基因/蛋白名称HDAC7A

修饰Phospho

别名HD7a; HDA7; HDAC7A;

数据库入口号Swiss-Prot#: Q8WUI4;
NCBI Gene#: 51564;
NCBI Protein#: NP_056216.2.

UniprotQ8WUI4

实际分子量103kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Western blotting: 1:500~1:1000

Western blot analysis of extracts from HeLa cells using HDAC7A (Phospho-Ser155) Antibody #11823.The lane on the right is treated with the antigen-specific peptide.
背景

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Walsh M.J., Submitted (FEB-2000).
Zelent A., Submitted (MAY-2003).
Sugano S., Nat. Genet. 36:40-45(2004)

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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