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位置: 首页 > 磷酸化抗体 > ITGB1 (Phospho-Tyr795) Antibody

ITGB1 (Phospho-Tyr795) Antibody#11824

ITGB1 (Phospho-Tyr795) Antibody
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产品总价:
产品详情

产品名称ITGB1 (Phospho-Tyr795) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous levels of ITGB1 only when phosphorylated at tyrosine 795.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of tyrosine 795(P-K-Y(p)-E-G) derived from Human ITGB1 .

基因/蛋白名称ITGB1

修饰Phospho

别名CD29; FNRB; ITB1;

数据库入口号Swiss-Prot#: P05556;
NCBI Gene#: 3688;
NCBI Protein#: NP_002202.2.

UniprotP05556

实际分子量140kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Western blotting: 1:500~1:1000

Western blot analysis of extracts from cos-7 cells (Lane 2), using ITGB1 (Phospho-Tyr795) Antibody #11824. The lane on the left is treated with antigen-specific peptide.
背景

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

Argraves W.S., J. Cell Biol. 105:1183-1190(1987).
Ota T., Nat. Genet. 36:40-45(2004).
Bechtel S., BMC Genomics 8:399-399(2007).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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