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位置: 首页 > 磷酸化抗体 > TPH2 (Phospho-Ser19) Antibody

TPH2 (Phospho-Ser19) Antibody#11828

TPH2 (Phospho-Ser19) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称TPH2 (Phospho-Ser19) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous levels of TPH2 only when phosphorylated at serine 19.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Serine 19(G-F-S(p)-L-D) derived from Human TPH2.

基因/蛋白名称TPH2

修饰Phospho

别名ADHD7; NTPH; TPH2;

数据库入口号Swiss-Prot#: Q8IWU9;
NCBI Gene#: 121278;
NCBI Protein#: NP_775489.2.

UniprotQ8IWU9

实际分子量56kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Western blotting: 1:500~1:1000

Western blot analysis of extracts from HepG2 cells using TPH2 (Phospho-Ser19) Antibody #11828.The lane on the right is treated with the antigen-specific peptide.
背景

This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.

Walther D.J., Science 299:76-76(2003).
Scherer S.E., Nature 440:346-351(2006).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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