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位置: 首页 > 磷酸化抗体 > CRMP-2 (Phospho-Ser522) Antibody

CRMP-2 (Phospho-Ser522) Antibody#11841

CRMP-2 (Phospho-Ser522) Antibody
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产品总价:
产品详情

产品名称CRMP-2 (Phospho-Ser522) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu

特异性The antibody detects endogenous levels of DPYSL2 only when phosphorylated at serine 522.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Serine 522(K-T-S(p)-P-A) derived from Human CRMP-2.

基因/蛋白名称CRMP-2

修饰Phospho

别名CRMP2; DPYL2; DRP2; ULIP-2;

数据库入口号Swiss-Prot#: Q16555;
NCBI Gene#: 1808;
NCBI Protein#: NP_001377.1.

UniprotQ16555

实际分子量62kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Western blotting: 1:500~1:1000

Western blot analysis of extracts from HuvEc cells (Lane 2), using CRMP-2 (Phospho-Ser522) Antibody #11841. The lane on the left is treated with antigen-specific peptide.
背景

CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.

Goshima Y., Nature 376:509-514(1995).
Hamajima N., Gene 180:157-163(1996).
Kitamura K., DNA Res. 6:291-297(1999).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com