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位置: 首页 > 磷酸化抗体 > PHB(Phospho-Tyr259) Antibody

PHB(Phospho-Tyr259) Antibody#11587

PHB(Phospho-Tyr259) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称PHB(Phospho-Tyr259) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of PHB only when phosphorylated at tyrosine 259.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of tyrosine 259 (I-T-Y(p)-L-P) derived from Human PHB.

基因/蛋白名称PHB

修饰Phospho

别名Prohibitin; PHB1

数据库入口号Swiss-Prot: P35232;
NCBI Gene: 5245;
NCBI Protein: NP_001268425.1.

UniprotP35232NCBIGene:5245

实际分子量29kd

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C

应用详情

 Western blotting: 1:500~1:1000

Western blot analysis of extracts from MCF, PC12, 293 and 3T3 cells using PHB (Phospho-Tyr259) Antibody #11587.
背景

 Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging. 

 

如果您使用该产品11587发表了文章,请通知我们,让我们可以引用您的文献。

et al,A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3 PBX1 and β-catenin ABCG2 signaling.In J Biomed Sci. On 2020 Mar 13; by Fang CH, Lin YT, et al..PMID: 32169072 , , (2020),
PMID: 32169072
et al,Olfactory Bulb Neuroproteomics Reveals a Chronological Perturbation of Survival Routes and a Disruption of Prohibitin Complex During Alzheimer's Disease Progression.Sci Rep on 2017 Aug 22 by Mercedes Lach茅n-Montes, Andrea Gonz谩lez-Morales,et al..PMID: 28831118, , (2017),
PMID: 28831118
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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