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MAPK14 Antibody#32026

MAPK14 Antibody
MAPK14 Antibody
MAPK14 Antibody
MAPK14 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称MAPK14 Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IHC,IF

种属反应性Human,Mouse,Rat

特异性The antibody detects endogenous level of total MAPK14 protein.

免疫原类型Peptide

免疫原描述A synthetic peptide of human p38 MAPK (NP_620581.1).

基因/蛋白名称MAPK14

别名MAPK14;CSBP;CSBP1;CSBP2;CSPB1;EXIP;Mxi2;PRKM14;PRKM15;RK;SAPK2A;p38;p38ALPHA;p38 MAPK

数据库入口号Uniprot:Q16539
GeneID:1432

UniprotQ16539

Gene ID1432

实际分子量41KDa

浓度1.0mg/ml

配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:500 - 1:1000
IHC 1:50 - 1:200
IF 1:50 - 1:100
Western blot analysis of extracts of various cell lines, using p38 MAPK antibody.
Immunohistochemistry of paraffin-embedded Human placenta using p38 MAPK Rabbit pAb.
Immunohistochemistry of paraffin-embedded Rat kidney using p38 MAPK Rabbit pAb.
Immunofluorescence analysis of NIH-3T3 cells using p38 MAPK antibody.
背景
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com