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Met(Ab-1234) Antibody#21220

Met(Ab-1234) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Met(Ab-1234) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total Met protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.1232~1236 (K-E-Y-Y-S) derived from Human Met.

基因/蛋白名称Met

别名HGF receptor; HGF-SF receptor; Met proto-oncogene tyrosine kinase; c-met; kinase Met

数据库入口号Swiss-Prot: P08581
NCBI Protein: NP_000236.2

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情
Predicted MW: 156kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from HepG2 cells using Met(Ab-1234) Antibody #21220 and the same antibody preincubated with blocking peptide.
背景
Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.

Gherardi E. et al. (2003).Proc Natl Acad Sci U S A. 100(21): 12039-12044.
Shiu SH. et al. (2001) Proc Natl Acad Sci U S A. 98(19): 10763-10768.
Hughes AL. et al. (2001) Genome Res. 11(5): 771-780.
Onuchic LF. et al. (2002) Am J Hum Genet. 70(5): 1305-1317.

如果您使用该产品21220发表了文章,请通知我们,让我们可以引用您的文献。

Luo W, Huang B, Li Z et al,MicroRNA-449a Is Downregulated in Non-Small Cell Lung Cancer and Inhibits Migration and Invasion by Targeting c-Met., PLoS ONE, 8(5): e64759 (2013),
PMID: 23734217
et al,MicroRNA-449a is downregulated in non-small cell lung cancer and inhibits migration and invasion by targeting c-Met. In PLoS One on 2013 May 29 by Wenting Luo, Bo Huang, et al..PMID: 23734217, , (2013),
PMID: 23734217
et al,miR-34a Inhibits Migration and Invasion by Down-Regulation of c-Met Expression in Human Hepatocellular Carcinoma Cells.In Cancer Lett on 2009 Mar 8 by Na Li, Hanjiang Fu,et al..PMID:19006648, , (2009),
PMID: 19006648
Na Li, Hanjiang Fu, Yi Tie et al,miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells., Cancer Letters, 275(1):44-53 (2008),
PMID: 19006648
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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