免费电话:400-9961-933
邮箱:techcn@signalwayantibody.com
欢迎光临本站
登录 注册 English
位置: 首页 > 抗体 > EGFR(Ab-869) Antibody

EGFR(Ab-869) Antibody#21222

EGFR(Ab-869) Antibody
EGFR(Ab-869) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称EGFR(Ab-869) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB IHC

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total EGFR protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.867~871 (K-E-Y-H-A) derived from Human EGFR.

基因/蛋白名称EGFR

别名 Receptor tyrosine-protein kinase ErbB-1; ERBB1;

数据库入口号Swiss-Prot: P00533
NCBI Protein: NP_005219.2

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

Predicted MW: 175kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using EGFR(Ab-869) Antibody #21222(left) or the same antibody preincubated with blocking peptide(right).
Western blot analysis of lysates from HUVEC, HUVEC EGF and Hela EGF,using EGFR Antibody.
背景

Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia

Gingras AC, et al. (1998) Genes Dev 12(4): 502-513.
Brugarolas J, et al. (2004) Genes Dev 18(23): 2893-2904.
Kumar V, et al. (2000) EMBO J 19(5): 1087-1097.
Moody CA, et al. (2005) J Virol 79(9): 5499-5506.
Burnett PE, et al. (1998) Proc Natl Acad Sci U S A 95(4): 1432-1437.

如果您使用该产品21222发表了文章,请通知我们,让我们可以引用您的文献。

et al,Secreted and O-GlcNAcylated MIF binds to the human EGF receptor and inhibits its activation.In Nat Cell Biol on 2015 Oct by Yanhua Zheng, Xinjian Li et al..PMID:26280537 , , (2015),
PMID: 26280537
et al,Aldosterone induces myofibroblast EGF secretion to regulate epithelial colonic permeability. In Am J Physiol Cell Physiol on 2013 May 1 by Llu茂sa Mir贸, Anna P茅rez-Bosque, et al..PMID:23467299 , , (2013),
PMID: 23467299
et al,Role of Proprotein Convertases in Prostate Cancer Progression.In Neoplasia on 2012 Nov by Fr茅d茅ric Couture, Fran莽ois D'Anjou,In Neoplasia on 2012 Nov by Fr茅d茅ric Couture, Fran莽ois D'Anjou, et al..PMID:23226097, , (2012),
PMID: 23226097
et al,EGFR-induced and PKC蔚 monoubiquitylation-dependent NF-魏B activation upregulates PKM2 expression and promotes tumorigenesis. In Mol Cell on 2012 Dec 14 by Weiwei Yang, Yan Xia, et al..PMID: 23123196, , (2012),
PMID: 23123196
et al,sZIP, an alternative splice variant of ZIP, antagonizes transcription repression and growth inhibition by ZIP. In J Biol Chem on 2010 May 7 by Wenhua Yu, Ruifang Li, et al..PMID: 20233718, , (2010),
PMID: 20233718
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com