产品详情
产品名称FGF10 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human,Mouse,Rat
特异性The antibody detects endogenous level of total FGF10 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human FGF10 (NP_004456.1).
基因/蛋白名称FGF10
别名FGF10
数据库入口号Uniprot:O15520
GeneID:2255
UniprotO15520
Gene ID2255
实际分子量27KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
背景
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.
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et al,KGF-2 Regulates STAP-2–Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation. In J Invest Dermatol
on 2022 Jul by Qingde Zhou, Jianxiang Gong,et al..PMID:34999107,
, (2022),
PMID: 34999107