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TIMP2 Antibody#32307

TIMP2 Antibody
TIMP2 Antibody
TIMP2 Antibody
TIMP2 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称TIMP2 Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IHC,IF

种属反应性Human,Mouse,Rat

特异性The antibody detects endogenous level of total TIMP2 protein.

免疫原类型Recombinant Protein

免疫原描述A synthetic peptide of human TIMP2 (NP_003246.1).

基因/蛋白名称TIMP2

别名TIMP2;CSC-21K;DDC8

数据库入口号Uniprot:P16035
GeneID:7077

UniprotP16035

Gene ID7077

实际分子量24KDa

浓度1.0mg/ml

配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using TIMP2 antibody.
Immunohistochemistry of paraffin-embedded rat kidney using TIMP2 Rabbit pAb.
Immunofluorescence analysis of C6 cells using TIMP2 antibody.
Immunofluorescence analysis of U-2 OS cells using TIMP2 antibody.
背景
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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025-58868422

Email Address

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