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Gab1(Ab-627) Antibody#21283

Gab1(Ab-627) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Gab1(Ab-627) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB

种属反应性Hu Ms

特异性The antibody detects endogenous level of total Gab1 protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.625~629 (V-E-Y-L-D) derived from Human Gab1.

基因/蛋白名称Gab1

别名Growth factor receptor bound protein 2-associated protein 1

数据库入口号Swiss-Prot: Q13480
NCBI Protein: NP_002030.2

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

Predicted MW: 110kd
Western blotting: 1:500~1:1000

Western blot analysis of extracts from A431 and MCF cells using Gab1 (Ab-627) Antibody #21283.
背景

The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

Anders Kallin, et al. (2004) J. Biol. Chem; 279: 17897 - 17904.
Hideto Kameda, et al. (2001) Cell Growth Differ; 12: 307.
Masaki Osawa, et al. (2002) J. Cell Biol; 158: 773.

如果您使用该产品21283发表了文章,请通知我们,让我们可以引用您的文献。

et al,EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation. IN Mol Cell.On 2018 Apr 19 by Lee JH, Liu R et al..PMID:29677490, , (2018),
PMID: 29677490
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com