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位置: 首页 > 标记抗体 > EMP1 Polyclonal Antibody Cy7 Conjugated

EMP1 Polyclonal Antibody Cy7 Conjugated#C00332Cy7

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产品详情

产品名称EMP1 Polyclonal Antibody Cy7 Conjugated

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Purified by Protein A.

应用IF(IHC-P)

种属反应性Ms Rt

免疫原描述KLH conjugated synthetic peptide aa 105-135 160 derived from mouse Emp1

标记Cy7

激发/发射波长743nm 767nm

基因/蛋白名称EMP1

别名TMP; I-8-9; Epithelial membrane protein 1; EMP-1; Tumor-associated membrane protein; Emp1

数据库入口号P54849

细胞定位Cell membrane

浓度1mg ml

配方Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

保存 Store at 4C for 12 months.

应用详情

IF:1:50-200

背景

Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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