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位置: 首页 > 抗体 > Synaptotagmin 1/2 (Ab-202/199) Antibody

Synaptotagmin 1/2 (Ab-202/199) Antibody#21293

Synaptotagmin 1/2 (Ab-202/199) Antibody
Synaptotagmin 1/2 (Ab-202/199) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Synaptotagmin 1/2 (Ab-202/199) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB IF

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total Synaptotagmin 1/2 protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.200~204/197~201 (R-K-T-L-N) derived from Human Synaptotagmin 1/2.

基因/蛋白名称Synaptotagmin 1/2

别名SYT1/2; SytI/II; Synaptotagmin I/II; P65; SYT

数据库入口号Swiss-Prot: P21579/Q8N9I0
NCBI Protein:NP_001129277.1/NP_001129976.1

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

Predicted MW: 46kd
Western blotting: 1:500~1:1000
Immunofluorescence: 1:100~1:200

Western blot analysis of extracts from Hela cells using Synaptotagmin 1/2(Ab-202/199) Antibody #21293 and the same antibody preincubated with blocking peptide.
Immunofluorescence staining of methanol-fixed Hela cells using Synaptotagmin 1/2(Ab-202/199) Antibody #21293.
背景

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse

Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10):3992-7.
Cnops L, et al. Cereb Cortex. 2008 May; 18(5):1221-31.
Lynch KL, et al. Mol Biol Cell. 2007 Dec; 18(12):4957-68.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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