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MRE11A Antibody#32712

MRE11A Antibody
MRE11A Antibody
MRE11A Antibody
MRE11A Antibody
是否有货: 有货
产品总价:
产品详情

产品名称MRE11A Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IHC,IF

种属反应性Human,Mouse,Rat

特异性The antibody detects endogenous level of total MRE11A protein.

免疫原类型Recombinant Protein

免疫原描述Recombinant fusion protein of human MRE11 (NP_005581.2).

基因/蛋白名称MRE11A

别名MRE11;ATLD;HNGS1;MRE11A;MRE11B

数据库入口号Uniprot:P49959
GeneID:4361

UniprotP49959

Gene ID4361

实际分子量81KDa

浓度1.0mg/ml

配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of K-562 cells, using MRE11 antibody.
Western blot analysis of extracts of various cell lines, using MRE11 antibody.
Immunohistochemistry of paraffin-embedded human colon carcinoma using MRE11 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human esophageal cancer using MRE11 Rabbit pAb.
背景
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com