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位置: 首页 > 抗体 > CLDN11 Antibody

CLDN11 Antibody#32740

CLDN11 Antibody
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产品总价:
产品详情

产品名称CLDN11 Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB

种属反应性Human, Mouse

特异性The antibody detects endogenous level of total CLDN11 protein.

免疫原类型Recombinant Protein

免疫原描述Recombinant fusion protein of human CLDN11 (NP_005593.2).

基因/蛋白名称CLDN11

别名CLDN11;OSP;OTM

数据库入口号Uniprot:O75508
GeneID:5010

UniprotO75508

Gene ID5010

实际分子量22kDa

浓度0.94 mg/ml

配方PBS with 0.05% proclin300,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情

WB 1:500 - 1:2000

Western blot analysis of various lysates, using CLDN11 antibody at 1:1000 dilution.
背景

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com