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位置: 首页 > 抗体 > a-catenin(Ab-641) Antibody

a-catenin(Ab-641) Antibody#21330

a-catenin(Ab-641) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称a-catenin(Ab-641) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB

种属反应性Hu Ms

特异性The antibody detects endogenous level of total a-catenin protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa. 639~643 (D-D-S-D-F) derived from Human a-catenin.

基因/蛋白名称a-catenin

别名Cadherin-associated protein; Alpha E-catenin; NY-REN-13 antigen

数据库入口号Swiss-Prot: P35221
NCBI Protein: NP_001894.2

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情
Predicted MW: 100kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from Hela and 293 cells using a-catenin(Ab-641) antibody #21330.
背景
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. May play a crucial role in cell differentiation.

Hwang, S.G. et al. (2005) J. Biol. Chem. 280, 12758-12765
Drees, F. et al. (2005) Cell 123, 903-915.
Yamada, S. et al. (2005) Cell 123, 889-901.
Kobielak, A. and Fuchs, E. (2004) Nat. Rev. Mol. Cell Biol. 5, 614-625.

如果您使用该产品21330发表了文章,请通知我们,让我们可以引用您的文献。

et al,伪-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism. In J Cell Sci on 2015 Mar 15 by David J Escobar, Ridhdhi Desai,et al..PMID:25653389, , (2015),
PMID: 25653389
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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