产品详情
产品名称DDX20 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human,Mouse,Rat
特异性The antibody detects endogenous level of total DDX20 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human DDX20 (NP_009135.4).
基因/蛋白名称DDX20
别名DDX20;DP103;GEMIN3
数据库入口号Uniprot:Q9UHI6
GeneID:11218
UniprotQ9UHI6
Gene ID11218
实际分子量110kDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IF 1:10 - 1:100
背景
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs.