免费电话:400-9961-933
邮箱:techcn@signalwayantibody.com
欢迎光临本站
登录 注册 English
位置: 首页 > 抗体 > Uba2 Antibody

Uba2 Antibody#33535

Uba2 Antibody
Uba2 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Uba2 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

应用WB IHC

种属反应性Hu

特异性The antibody detects endogenous levels of total Uba2 protein.

免疫原类型Peptide

免疫原描述Synthesized peptide derived from C-terminal of human Uba2.

基因/蛋白名称Uba2

别名ANTHRACYCLINE-associated resistance ARX; ARX; EC 6.3.2.-; SUMO-1 activating enzyme subunit 2; UBA2

数据库入口号Swiss-Prot: Q9UBT2
NCBI Gene ID: 10054

UniprotQ9UBT2

实际分子量71kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Western blot analysis of extracts from 293 cells, treated with UV (5mins), using Uba2 antibody #33535.
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Uba2 antibody #33535.
背景
The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Mark H. L. Lambermon, Mol. Cell. Biol., Jun 2002; 22: 4346 - 4357.
Kyoung-Seok Ryu, J. Biol. Chem., Sep 2003; 278: 36621 - 36627.
R. Jrgen Dohmen, J. Biol. Chem., Jul 1995; 270: 18099.
Yoshiaki Azuma, FASEB J, Jun 2001; 10.1096.

如果您使用该产品33535发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com