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位置: 首页 > 抗体 > SOX2 Antibody

SOX2 Antibody#21425

SOX2 Antibody
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产品总价:
产品详情

产品名称SOX2 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total SOX2 protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.76~80 (G-A-E-W-K) derived from SOX2

基因/蛋白名称SOX2

别名Transcription factor SOX-2

数据库入口号Swiss-Prot: P48431
NCBI Protein: NP_003097.1

UniprotP48431

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

Predicted MW: 35kd
Western blotting: 1:1000

Western blot analysis of extracts from human Umbilical cord mesenchymal stem cell using SOX2 Antibody #21425.
背景

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency

Yuan H, et al. Genes Dev. 1995 Nov 1;9(21):2635-45
Muta M, et al. Genes Cells 2002 Aug;7(8):791-805
Tomioka M, et al. Nucleic Acids Res. 2002 Jul 15; 30(14): 3202-3213.

如果您使用该产品21425发表了文章,请通知我们,让我们可以引用您的文献。

et al,Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness.In BMC Cancer on 2015 Oct 24 by Jianguo Xue , Yuan Zhu et al..PMID: 26498753, , (2015),
PMID: 26498753
et al,Activation of mesenchymal stem cells by macrophages prompts human gastric cancer growth through NF-魏B pathway.In PLoS One on 2014 May 13 by Tingting Yang , Xu Zhang et al..PMID:24824968, , (2014),
PMID: 24824968
et al,SALL4, a novel marker for human gastric carcinogenesis and metastasis.In Oncogene on 2014 Nov 27 by L Zhang , Z Xu et al..PMID:24276240, , (2014),
PMID: 24276240
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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