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位置: 首页 > 磷酸化抗体 > HNF4a(Phospho-Ser304) Antibody

HNF4a(Phospho-Ser304) Antibody#11043

HNF4a(Phospho-Ser304) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称HNF4a(Phospho-Ser304) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of HNF4a only when phosphorylated at serine 304.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of serine 304 (L-R-S(p)-Q-V)derived from Human HNF4a.

基因/蛋白名称HNF4a

修饰Phospho

别名HNF4; TCF; MODY; HNF4A;

数据库入口号Swiss-Prot: P41235
NCBI Protein: NP_000448.3

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情
Predicted MW: 52kd
Western blotting: 1:1000
Western blot analysis of extracts from Hela cells untreated or treated with Anisomyclin using HNF4a(Phospho-Ser304) Antibody #11043.
背景
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes,including hepatocyte nuclear factor 1 a, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants.

Kritis A.A,et al.Gene 173:275-280(1996)
Drewes T,et al.Mol. Cell. Biol. 16:925-931(1996)
Yamagata K,et al.Nature 384:458-460(1996)
Tanaka T,et al.Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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