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位置: 首页 > 抗体 > ZMY11 Antibody

ZMY11 Antibody #33894

ZMY11 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称ZMY11 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

应用IHC

种属反应性Hu Ms

特异性The antibody detects endogenous levels of total ZMY11 protein.

免疫原类型Peptide

免疫原描述Synthesized peptide derived from internal of human ZMY11.

基因/蛋白名称ZMY11

别名Zinc finger MYND domain-containing protein 11; Adenovirus 5 E1A-binding protein; BS69 protein; ZMYND11; BS69

数据库入口号Swiss-Prot: Q15326
NCBI Gene ID: 10771

UniprotQ15326

实际分子量66kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情

Immunohistochemistry: 1:50~1:100
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ZMY11 antibody #33894.
背景
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) By similarity. Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

Hateboer G., EMBO J. 14:3159-3169(1995).
Deloukas P., Nature 429:375-381(2004).
Matsuoka S., Science 316:1160-1166(2007).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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