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Oct-1 Antibody#21674

Oct-1 Antibody
Oct-1 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Oct-1 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB IF

种属反应性Hu Ms

特异性The antibody detects endogenous levels of total Oct-1 protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.270~274(T-P-K-R-I) derived from Human Oct-1.

基因/蛋白名称Oct-1

别名1-Oct; OTF1; oct-1B

数据库入口号Swiss-Prot: P14859
NCBI Protein: NP_001185712.1

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20℃ for long term preservation (recommended). Store at 4°C for short term use.

应用详情
Predicted MW: 90kd
Western blotting: 1:500~1:1000
Immunofluorescence:1:100~1:200
 
Western blot analysis of extracts from JK, HepG2 and 293 cells using Oct-1 Antibody #21674.
Immunofluorescence staining of methanol-fixed NCI-h446 cells showing cytoplasmic staining using Oct-1 Antibody #21674.
背景

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

Prefontaine G.G., Walther R., Giffin W. J. Biol. Chem. 274:26713-26719(1999)
Mahajan S.S., Wilson A.C. Mol. Cell. Biol. 20:919-928(2000)

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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400-9961-933
025-58868422

Email Address

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