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C/EBPb Antibody#21675

C/EBPb Antibody
是否有货: 有货
产品总价:
产品详情

产品名称C/EBPb Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB

种属反应性Hu

特异性The antibody detects endogenous levels of total C/EBPb protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.336~340(E-P-L-L-A) derived from Human C/EBPb.

基因/蛋白名称C/EBPb

别名IL6DBP; CRP2; TCF5; LAP; NF-IL6

数据库入口号Swiss-Prot: P17676
NCBI Protein: NP_005185.2

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情
Predicted MW: 36kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from Rat brain, Mouse brain tissue and 293 cells using C/EBPb Antibody #21675.
背景
Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation

Buck M., Poli V., Hunter T., Chojkier M. Mol. Cell 8:807-816(2001)
Gauci S., Helbig A.O., Slijper M., Krijgsveld J. Mohammed S.Anal. Chem. 81:4493-4501(2009)

如果您使用该产品21675发表了文章,请通知我们,让我们可以引用您的文献。

et al,Clock represses preadipocytes adipogenesis via GILZ .In J Cell Physiol.On 2018 Aug by Zhu Z, Xu L et al..PMID: 29278648, , (2018),
PMID: 29278648
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com