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TLR4 Antibody#35577

TLR4 Antibody
TLR4 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称TLR4 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antigen affinity purification.

应用WB IHC

种属反应性Hu

特异性The antibody detects endogenous levels of total TLR4 protein.

免疫原类型Recombinant Protein

免疫原描述Fusion protein corresponding to a region derived from internal residues of human toll-like receptor 4

基因/蛋白名称TLR4

别名TOLL; CD284; TLR-4; ARMD10

数据库入口号Swiss-Prot#: O00206
NCBI Gene ID: 7099
Gene Accssion: BC117422

UniprotO00206

实际分子量96kd

浓度1.1mg/ml

配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Gel: 6%SDS-PAGE
Lysate: 60ug K562 cell
Primary antibody: 1/550 dilution
Secondary antibody dilution: 1/8000
Exposure time: 1 minute
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #35577 at dilution 1/25.
背景
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

如果您使用该产品35577发表了文章,请通知我们,让我们可以引用您的文献。

et al,Anti-inflammatory Mechanism of Bone Marrow Mesenchymal Stem Cell Transplantation in Rat Model of Spinal Cord Injury.In Cell Biochem Biophys.On 2015 Apr by Han D, Wu C et al..PMID:25388837, , (2015),
PMID: 25388837
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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